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Entries Tagged as 'Drug Abuse'

Brain Neurotransmitters and Addiction

September 5th, 2007 · No Comments

Electrical signals in the brain are sent using chemicals called neurotransmitters. All addictive drugs affect the production, release, or elimination of neurotransmitters. The major Neurotransmitters implicated in addiction are noted below.

Serotonin

Serotonin (5-hydroxytryptamine or 5-HT) is synthesized from dietary tryptophan and its primary function is regulation of sleep and mood. Low levels of serotonin have been associated with mood disorders such as depression.

Medications called specific serotonin reuptake inhibitors (SSRIs), such as Prozac and Zoloft, increase serotonin levels but can be very dangerous. You should consider taking the essential amino acid trytophan instead. Check with a holistic doctor for advice.

Norepinephrine (NE)

NE’s common function is associated with arousal and alertness. It is synthesized from the essential amino acid tyrosine. The levels of NE fluctuate throughout the day and therefore there are periods when we feel more awake and alert, while at other times we are tired and sleepy.

Certain drugs of abuse, such as stimulants or “uppers”, increase alertness and arousal and cause talkativeness, restlessness, and agitation because of their action on NE systems.

Dopamine

Dopamine release gives us the experience of pleasure and therefore causes us to want to repeat the behaviors necessary to acquire the reward in the future.

It’s interesting that amphetamine and cocaine both increase the amount of dopamine. However, cocaine achieves this action by preventing dopamine reuptake, while amphetamine helps to release more dopamine.

So, these drugs with similar effects produce their actions through entirely different processes. In turn, addiction to the two drugs may call for somewhat different types of addiction treatment.

GABA

Gamma aminobutyric acid (GABA) is synthesized from glutamate (an amino acid) and is found in very high concentrations throughout the brain. It is considered an “inhibitory neurotransmitter”. Because GABA has inhibitory effects on neurons, any drug that increases the actions of GABA will decrease general brain activity and can be considered a “downer” or depressant. Depressants include alcohol, sleeping pills such as Ambien, muscle relaxants such as Valium, and barbiturates such as Secobarbital. Some depressants are very powerful and can cause coma or death.

The Most Addictive Drugs

Different drugs have different effects on the neurotransmitters. For instance, cocaine and methamphetamine are much more addicting than THC (marijuana) because they increase dopamine levels more quickly and to a greater extent.

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Tags: Drugs and Brain Disorders · Street Drugs

ADHD and Street Drugs

August 7th, 2007 · No Comments

Researchers have generally known that people with ADHD are more likely than others to smoke cigarettes and abuse alcohol, marijuana, cocaine and other drugs.

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Tags: Drugs and Brain Disorders · Street Drugs

Drugs, Alcohol and ADD

July 15th, 2007 · No Comments

Many people with ADD self-medicate (treat their underlying problems) with substances as a way to feel more focused, more together, less anxious, less depressed, less overwhelmed, and just generally better.

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Tags: Alcohol Addiction · Drugs and Brain Disorders · Marijuana Addiction

Marijuana Use Damages The Brain

June 2nd, 2007 · No Comments

In studies of patients who had smoked marijuana, Dr. Daniel Amen found significant changes in brain activity, especially those who were heavy users. Decreased brain activity was found in the prefrontal cortex and temporal lobes.

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Tags: Drugs and Brain Disorders · Marijuana Addiction

SPECT Brain Scans

May 31st, 2007 · No Comments

The scans of brains of people who have abused drugs showed abnormalities.

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Tags: Drugs and Brain Disorders

Get Rid of White Sugar, White Flour, White Rice and . . .

May 18th, 2007 · No Comments

Get rid of white sugar, white flour, white rice, and white oils to help keep your blood sugar under control and maintain a biochemical balance within the brain according to Michael Lesser, M.D., a nutritional psychiatrist and author of The Brain Chemistry Plan. He is one of the pioneers in the development of orthomolecular psychiatry and medicine.

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Tags: Drugs and Brain Disorders · Sugar Addiction

Inhalant Facts

May 3rd, 2007 · No Comments

Inhalants are volatile substances found in many household products, such as oven cleaners, gasoline, spray paints, and other aerosols. Some people inhale the vapors from these products on purpose.

Why would anyone do this? Because the chemicals in these vapors can change the way the brain works, and those changes can make people feel very happy for a short time.

But inhalants are extremely toxic and can do a great deal of harm.
 

Chemicals Don’t Go Away When You Exhale

Inhalant vapors often contain more than one chemical. Some leave the body quickly, but others are absorbed by fatty tissues in the brain and nervous system and can stay there for a long time.

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Tags: Drugs and Brain Disorders · Street Drugs

Meth and the Brain

May 2nd, 2007 · No Comments

Speed, meth, chalk, crystal, ice, glass. These are all names for the drug methamphetamine. It comes in many different forms and is snorted, swallowed, injected, or smoked. The smokable form is known as “ice” or “crystal,” due to its appearance.

Meth is a powerful street drug. It acts by changing how the brain works. It also speeds up many functions in the body. It has a chemical structure that is similar to another drug called amphetamine. Methamphetamine can cause lots of harmful things, including inability to sleep, paranoia, aggressiveness, and hallucinations.

How Does Methamphetamine Cause its Effects?

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Tags: Drugs and Brain Disorders · Street Drugs

What Are Some Effects of Specific Abused Substances?

May 1st, 2007 · No Comments

Nicotine is an addictive stimulant found in cigarettes and other forms of tobacco. Tobacco smoke increases a user’s risk of cancer, emphysema, bronchial disorders, and cardiovascular disease. The mortality rate associated with tobacco addiction is staggering. Tobacco use killed approximately 100 million people during the 20th century and, if current smoking trends continue, the cumulative death toll for this century has been projected to reach 1 billion.

Marijuana is the most commonly abused illicit substance. This drug impairs short-term memory and learning, the ability to focus attention, and coordination. Marijuana also increases heart rate, can harm the lungs, and can cause psychosis in those at risk.

Alcohol consumption can damage the brain and most body organs. Areas of the brain that are especially vulnerable to alcohol-related damage are the cerebral cortex (largely responsible for our higher brain functions, including problem solving and decision making), the hippocampus (important for memory and learning), and the cerebellum (important for movement coordination).

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Tags: Drug Abuse

Does Drug Abuse Cause Mental Disorders, or Vice Versa?

April 28th, 2007 · No Comments

Drug abuse and brain disorders often co-exist. In some cases, mental diseases may precede addiction; in other cases, drug abuse may trigger or exacerbate mental disorders, particularly in individuals with specific vulnerabilities.

What are the medical consequences of drug addiction?

Individuals who suffer from addiction often have one or more accompanying medical issues, including lung and cardiovascular disease, stroke, cancer, and mental disorders. Imaging scans, chest x-rays, and blood tests show the damaging effects of drug abuse throughout the body. For example, tests show that smoking causes cancer of the mouth, throat, larynx, blood, lungs, stomach, pancreas, kidney, bladder, and cervix. In addition, some drugs of abuse, such as inhalants, are toxic to nerve cells and may damage or destroy them either in the brain or the peripheral nervous system.

What harmful consequences to others result from drug addiction?

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Tags: Drugs and Brain Disorders · Smoking - Nicotine Addiction